Give Patients the Relief They’ve Been Searching For

For patients suffering from leg cramps, restless legs syndrome (RLS), and arthritis or other joint issues, finding relief that’s both safe and effective can be challenging.1-3

For Muscle Cramps
and Spasms

NEW! For Joint Discomfort
and Inflammation

While prescription medications are beneficial in many cases, they can come with side effects, risks, and limitations—particularly regarding opioids and non-steroidal anti-inflammatory drugs (NSAIDs) in the senior population:

  • Due to the increased risk of opioid-related falls and the rise in opioid misuse among the elderly, the CDC now urges clinicians to consider non-opioid options to manage chronic pain.4,5
  • In recent years, the FDA strengthened its warning on the increased risk of heart attack or stroke with prolonged use of non-aspirin NSAIDs.6 Plus, NSAIDs are contraindicated in patients with chronic kidney disease7—which affects nearly 40% of adults 60 and older8—and in those taking anticoagulants.9

Theraworx Relief Products Are Different

Our line of Theraworx Relief products for patients suffering from muscle cramps, symptoms associated with RLS, and inflammation associated with arthritis or other joint conditions are:

  • Safe and effective topical solutions
  • Non-centrally acting
  • Non-addictive
  • Non-cannabis, non-CBD oil

Select one of the following tabs to learn more about our Theraworx Relief solutions:

Our clinically proven and published, locally and non-centrally acting, fast-acting topical solution:

Theraworx Relief 7.1 oz Foam
  • REDUCES the severity of symptoms associated with RLS
  • PREVENTS muscle cramps and spasms when used daily
  • RELEASES muscle tightness
  • RELIEVES muscle soreness

With a unique antispasmodic and muscle relaxant mechanism of action, Theraworx Relief for Muscle Cramps and Spasms may serve as a first-line alternative to prescribed centrally acting agents when patients experience dose-limiting effects. For more information about how Theraworx Relief for Muscle Cramps and Spasms works, contact us.

Clinical Evidence

In clinical trials, Theraworx Relief for Muscle Cramps and Spasms demonstrated clinically significant results in studies involving RLS and nocturnal muscle cramps:

  • In an Omega Clinical Research study including 35 patients diagnosed with moderate-to-very severe RLS, 60% of participants using Theraworx Relief for Muscle Cramps and Spasms experienced a 50% or greater reduction in severity of symptoms as documented using the IRLS assessment tool.10
  • In a study including 49 patients diagnosed with chronic nocturnal muscle cramps and spasms, 60% of participants using Theraworx Relief for Muscle Cramps and Spasms experienced significant reduction in the incidence and severity of nocturnal muscle cramps, improvements in self-reported quality of life and sleep quality, and a reduction in depressive incidents.11
A Companion Product

Theraworx Relief for Muscle Cramps and Spasms has also been shown to work well as a companion product to certain prescription drugs. According to the latest NPR-Truven Health Analytics Health Poll, nearly 1/3 of people have stopped taking their prescription medications without telling their doctors. Of them, 29% said they’ve stopped due to side effects.12

Muscle cramps happen to be a reported side effect of hundreds of prescription medications, from intravenous iron sucrose and conjugated estrogens to statins and diuretics.1,13 Additionally, certain medications can cause or exacerbate RLS symptoms.14

A Convenient Option

What’s more, our safe and gentle formulation is not sticky or greasy, and it’s a convenient option for many patients. While some products may require up to 12 tablets a day to simply relieve symptoms,15 Theraworx Relief for Muscle Cramps and Spasms can prevent muscle cramps and spasms with just a few simple applications a day. Learn more about dosage guidelines.

Theraworx Relief 7.1 oz Spray and Foam

Theraworx Relief for Joint Discomfort and Inflammation—studied in patients with moderate-to-severe joint inflammation—is the only dual-modality, topical anti-inflammatory therapy system for the relief of arthritic, inflamed, sore, or overused joints.

The two-part system combining the fast-acting Theraworx Relief Joint Discomfort and Inflammation Foam plus medical-grade compression:

  • PROVIDES MAXIMUM RELIEF for arthritic, inflamed, sore, or overused joints
  • INCREASES range of motion
  • IMPROVES daily function

While maximum joint relief is achieved with the dual-modality therapy system, the foam and compression are also beneficial on their own.

Medical-Grade Compression Glove and Knee Sleeve
  • PROVIDES SUPPORT
  • RELIEVES stiffness and soreness
  • REDUCES pain and soreness due to reduction of swelling joints

What’s more, every compression glove and sleeve is made with silver fibers and is odor-resistant.

Our Glove vs. Braces
Theraworx Relief Dual Modality (Hand) Futuro ACE
Indication for Discomfort Mild Moderate Severe Mild Moderate Severe Mild Moderate Severe
Medical-grade compression Yes No No
Clinically tested in moderate-to-severe sufferers Yes No No
Glove covers proximal interphalangeal joints Yes No No
Glove covers metacarpophalangeal joints Yes Yes Yes
Wear time Night (or day) No No
Machine washable Yes No No
Paired with a topical anti-inflammatory foam Yes No No
Our Knee Sleeve vs. Braces
Theraworx Relief Dual Modality (Hand) Futuro ACE
Indication for Discomfort Mild Moderate Severe Mild Moderate Severe Mild Moderate Severe
Medical-grade compression Yes No No
Clinically tested in moderate-to-severe sufferers Yes No No
Purpose Joint inflammation, stiffness, soreness Stability, mild support Stability, mild support
Wear time Night (or day) Day Day
Machine washable Yes No No
Paired with a topical anti-inflammatory foam Yes No No
Theraworx Relief Joint Discomfort and Inflammation Foam
  • RELIEVES arthritic, inflamed, sore, or overused joints
  • INCREASES range of motion
  • IMPROVES daily function

Plus, our safe and gentle formulation is easy to use, not sticky or greasy, and a convenient option for many patients.

Hear From the Management Team

Ralph Lombardo, SVP
Steve Woody, CEO

Want More?

If you are a healthcare professional and would like to request clinical trial results, receive general information, or get Theraworx Relief on your shelves, contact us today.

REFERENCES:

  1. Allen RE, Kirby KA. Nocturnal leg cramps. Am Fam Physician. 2012;86(4):350-355.
  2. WebMD website. Treatments for restless legs syndrome. https://www.webmd.com/brain/restless-legs-syndrome/restless-leg-syndrome-treatment. Accessed April 11, 2019.
  3. Dowell D, Haegerich TM, Chou R. CDC guideline for prescribing opioids for chronic pain — United States, 2016. MMWR Recomm Rep. 2016;65(No. RR-1):1–49. DOI: http://dx.doi.org/10.15585/mmwr.rr6501e1.
  4. U.S. Pharmacist website. Special considerations for opioid use in elderly patients with chronic pain. https://www.uspharmacist.com/article/special-considerations-for-opioid-use-in-elderly-patients-with-chronic-pain. Accessed April 11, 2019.
  5. HCUP website. Statistical Brief #244. Opioid-related inpatient stays and emergency department visits among patients aged 65 years and older, 2010 and 2015.
  6. FDA website. FDA Drug Safety Communication: FDA strengthens warning that non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) can cause heart attacks or strokes. https://www.fda.gov/Drugs/DrugSafety/ucm451800.htm. Accessed April 26, 2019.
  7. American Academy of Family Physicians website. Choosing Wisely: Avoid nonsteroidal anti-inflammatory drugs (NSAIDs) in individuals with hypertension or heart failure or chronic kidney disease of all causes, including diabetes. https://www.aafp.org/afp/recommendations/viewRecommendation.htm?recommendationId=36. Accessed April 26, 2019.
  8. Mallappallil M, Friedman EA, Delano BG, et al. Chronic kidney disease in the elderly: evaluation and management. Clin Pract (Lond). 2014;11(5):525–535. doi:10.2217/cpr.14.46.
  9. Pharmacy Times® website. Oral anticoagulants and NSAIDs, SSRIs, or SNRIs. https://www.pharmacytimes.com/publications/issue/2017/december2017/oral-anticoagulants-and-nsaids-ssris-or-snris. Accessed April 26, 2019.
  10. Fried D, Renzulli J, Mega A, Topp R, Pezullo J. Restless legs syndrome: the efficacy of a non-systemic, non-centrally acting topical treatment. Omega Clinical Research – submitted for publication.
  11. Topp R. Effect of Theraworx/[pH]Uel on night-time leg cramps and spasm symptoms. Sport and Spine Rehab Clinical Research Foundation. June 2017.
  12. NPR website. Shots Health News From NPR. Why do people stop taking their meds? Cost is just one reason. https://www.npr.org/sections/health-shots/2017/09/08/549414152/why-do-people-stop-taking-their-meds-cost-is-just-one-reason. Accessed April 11, 2019.
  13. Grandner MA, Winkelman JW. Nocturnal leg cramps: prevalence and associations with demographics, sleep disturbance symptoms, medical conditions, and cardiometabolic risk factors. PLoS ONE. 2017;12(6). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460850/. Accessed April 11, 2019.
  14. Medscape website. Restless legs syndrome. https://emedicine.medscape.com/article/1188327-overview?pa=X8cK751reBLkQHumBlaS7uj1ahok2I99zZS7FDPyOZZmJlFKiddE%2BB79UeoqnUM3LY5dv1GLa9D%2BIsS%2BmSdmuodcsLcCFocixa0acF7OcZE%3D#a4. Accessed April 11, 2019.
  15. Hyland’s website. Hyland’s leg cramps. Directions. http://www.hylands.com/products/hylands-leg-cramps. Accessed April 11, 2019.
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